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sting pathway sampler kit  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc sting pathway sampler kit
    FTZ@Fu SANs induce immunogenic cell death and potentiate immune checkpoint blockage therapy. ( A ) CLSM images of CRT expression in MDA-MB-231 cells after being treated with FZ, FT, FTZ, and FTZ@Fu MNCs (5 µg/ml) for 24 h. Bar = 100 μm. ( B ) Extracellular ATP release by MDA-MB-231 cells treated with FTZ@Fu (0–20 µg/ml) (left panel) or different MNC formulations (right panel). ( C ) CLSM images of γH2AX expression in MDA-MB-231 cells after being treated with MNCs (5 µg/ml) for 24 h. Bar =100 μm. Quantification of γH2AX-positive cells is shown in the right panel. ( D ) Western blot showing activation of the <t>sGAS/STING</t> <t>pathway</t> in MDA-MB-231 cells treated with MNCs. ( E ) Flow cytometric analysis of dendritic cell maturation (left panel), and quantitative data are shown in the right panel. ( F ) Quantification of dendritic cell-mediated tumor cell phagocytosis by a flow cytometric analysis
    Sting Pathway Sampler Kit, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 20 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sting pathway sampler kit/product/Cell Signaling Technology Inc
    Average 94 stars, based on 20 article reviews
    sting pathway sampler kit - by Bioz Stars, 2026-03
    94/100 stars

    Images

    1) Product Images from "Fucoidan-decorated metal-zoledronic acid nanocomplexes suppress tumor metastasis by inducing ferroptotic cell death and enhancing cancer immunotherapy"

    Article Title: Fucoidan-decorated metal-zoledronic acid nanocomplexes suppress tumor metastasis by inducing ferroptotic cell death and enhancing cancer immunotherapy

    Journal: Journal of Nanobiotechnology

    doi: 10.1186/s12951-025-03473-0

    FTZ@Fu SANs induce immunogenic cell death and potentiate immune checkpoint blockage therapy. ( A ) CLSM images of CRT expression in MDA-MB-231 cells after being treated with FZ, FT, FTZ, and FTZ@Fu MNCs (5 µg/ml) for 24 h. Bar = 100 μm. ( B ) Extracellular ATP release by MDA-MB-231 cells treated with FTZ@Fu (0–20 µg/ml) (left panel) or different MNC formulations (right panel). ( C ) CLSM images of γH2AX expression in MDA-MB-231 cells after being treated with MNCs (5 µg/ml) for 24 h. Bar =100 μm. Quantification of γH2AX-positive cells is shown in the right panel. ( D ) Western blot showing activation of the sGAS/STING pathway in MDA-MB-231 cells treated with MNCs. ( E ) Flow cytometric analysis of dendritic cell maturation (left panel), and quantitative data are shown in the right panel. ( F ) Quantification of dendritic cell-mediated tumor cell phagocytosis by a flow cytometric analysis
    Figure Legend Snippet: FTZ@Fu SANs induce immunogenic cell death and potentiate immune checkpoint blockage therapy. ( A ) CLSM images of CRT expression in MDA-MB-231 cells after being treated with FZ, FT, FTZ, and FTZ@Fu MNCs (5 µg/ml) for 24 h. Bar = 100 μm. ( B ) Extracellular ATP release by MDA-MB-231 cells treated with FTZ@Fu (0–20 µg/ml) (left panel) or different MNC formulations (right panel). ( C ) CLSM images of γH2AX expression in MDA-MB-231 cells after being treated with MNCs (5 µg/ml) for 24 h. Bar =100 μm. Quantification of γH2AX-positive cells is shown in the right panel. ( D ) Western blot showing activation of the sGAS/STING pathway in MDA-MB-231 cells treated with MNCs. ( E ) Flow cytometric analysis of dendritic cell maturation (left panel), and quantitative data are shown in the right panel. ( F ) Quantification of dendritic cell-mediated tumor cell phagocytosis by a flow cytometric analysis

    Techniques Used: Expressing, Western Blot, Activation Assay



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    FTZ@Fu SANs induce immunogenic cell death and potentiate immune checkpoint blockage therapy. ( A ) CLSM images of CRT expression in MDA-MB-231 cells after being treated with FZ, FT, FTZ, and FTZ@Fu MNCs (5 µg/ml) for 24 h. Bar = 100 μm. ( B ) Extracellular ATP release by MDA-MB-231 cells treated with FTZ@Fu (0–20 µg/ml) (left panel) or different MNC formulations (right panel). ( C ) CLSM images of γH2AX expression in MDA-MB-231 cells after being treated with MNCs (5 µg/ml) for 24 h. Bar =100 μm. Quantification of γH2AX-positive cells is shown in the right panel. ( D ) Western blot showing activation of the <t>sGAS/STING</t> <t>pathway</t> in MDA-MB-231 cells treated with MNCs. ( E ) Flow cytometric analysis of dendritic cell maturation (left panel), and quantitative data are shown in the right panel. ( F ) Quantification of dendritic cell-mediated tumor cell phagocytosis by a flow cytometric analysis
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    FTZ@Fu SANs induce immunogenic cell death and potentiate immune checkpoint blockage therapy. ( A ) CLSM images of CRT expression in MDA-MB-231 cells after being treated with FZ, FT, FTZ, and FTZ@Fu MNCs (5 µg/ml) for 24 h. Bar = 100 μm. ( B ) Extracellular ATP release by MDA-MB-231 cells treated with FTZ@Fu (0–20 µg/ml) (left panel) or different MNC formulations (right panel). ( C ) CLSM images of γH2AX expression in MDA-MB-231 cells after being treated with MNCs (5 µg/ml) for 24 h. Bar =100 μm. Quantification of γH2AX-positive cells is shown in the right panel. ( D ) Western blot showing activation of the <t>sGAS/STING</t> <t>pathway</t> in MDA-MB-231 cells treated with MNCs. ( E ) Flow cytometric analysis of dendritic cell maturation (left panel), and quantitative data are shown in the right panel. ( F ) Quantification of dendritic cell-mediated tumor cell phagocytosis by a flow cytometric analysis
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    Image Search Results


    FTZ@Fu SANs induce immunogenic cell death and potentiate immune checkpoint blockage therapy. ( A ) CLSM images of CRT expression in MDA-MB-231 cells after being treated with FZ, FT, FTZ, and FTZ@Fu MNCs (5 µg/ml) for 24 h. Bar = 100 μm. ( B ) Extracellular ATP release by MDA-MB-231 cells treated with FTZ@Fu (0–20 µg/ml) (left panel) or different MNC formulations (right panel). ( C ) CLSM images of γH2AX expression in MDA-MB-231 cells after being treated with MNCs (5 µg/ml) for 24 h. Bar =100 μm. Quantification of γH2AX-positive cells is shown in the right panel. ( D ) Western blot showing activation of the sGAS/STING pathway in MDA-MB-231 cells treated with MNCs. ( E ) Flow cytometric analysis of dendritic cell maturation (left panel), and quantitative data are shown in the right panel. ( F ) Quantification of dendritic cell-mediated tumor cell phagocytosis by a flow cytometric analysis

    Journal: Journal of Nanobiotechnology

    Article Title: Fucoidan-decorated metal-zoledronic acid nanocomplexes suppress tumor metastasis by inducing ferroptotic cell death and enhancing cancer immunotherapy

    doi: 10.1186/s12951-025-03473-0

    Figure Lengend Snippet: FTZ@Fu SANs induce immunogenic cell death and potentiate immune checkpoint blockage therapy. ( A ) CLSM images of CRT expression in MDA-MB-231 cells after being treated with FZ, FT, FTZ, and FTZ@Fu MNCs (5 µg/ml) for 24 h. Bar = 100 μm. ( B ) Extracellular ATP release by MDA-MB-231 cells treated with FTZ@Fu (0–20 µg/ml) (left panel) or different MNC formulations (right panel). ( C ) CLSM images of γH2AX expression in MDA-MB-231 cells after being treated with MNCs (5 µg/ml) for 24 h. Bar =100 μm. Quantification of γH2AX-positive cells is shown in the right panel. ( D ) Western blot showing activation of the sGAS/STING pathway in MDA-MB-231 cells treated with MNCs. ( E ) Flow cytometric analysis of dendritic cell maturation (left panel), and quantitative data are shown in the right panel. ( F ) Quantification of dendritic cell-mediated tumor cell phagocytosis by a flow cytometric analysis

    Article Snippet: Specific primary antibodies are as following: GCLC (ab53179, Abcam), GPX4 (GTX54095, GeneTex), NCOA4 (#66849, Cell Signaling Technology), LC3B (#83506, Cell Signaling Technology), FTH1 (#4393, Cell Signaling Technology), and a STING pathway sampler kit (#38866, Cell Signaling Technology).

    Techniques: Expressing, Western Blot, Activation Assay